OMB M-25-21 — Accelerating Federal Use of AI through Innovation, Governance, and Public Trust

OMB Memorandum M-25-21 (Apr. 3, 2025) is the Trump-era replacement for M-24-10. It sets the binding rule for how federal agencies use AI — requiring CAIO designations, AI use inventories, and risk-management practices for rights/safety-impacting AI, with a pro-innovation framing.

Technical detail

M-25-21 implements EO 14179. Requires: (1) agency CAIO; (2) public AI use case inventory updated annually; (3) minimum-risk-management practices for high-impact AI (covering pre-deployment testing, ongoing monitoring, opt-out where feasible, public notice); (4) CIO/CAIO governance councils. Successor to M-24-10 (rescinded).

Who is protected: Public interacting with federal-agency AI

Who must comply: All federal executive-branch agencies

Key facts

More AI rules in United States

• FTC Act Section 5 (unfair/deceptive AI) · In effect
• TAKE IT DOWN Act · In effect
• FCRA (AI in credit & background checks) · In effect
• ECOA / Regulation B (AI credit discrimination) · In effect
• Title VII / ADA (AI hiring) · In effect
• COPPA + 2025 Rule (childrens data) · In effect

Related government use of AI rules elsewhere

• SB 53 (Frontier AI Safety) · In effect
• RAISE Act · Enacted (not yet in effect)
• TRAIGA · In effect
• Kentucky SB 4 (AI Governance) · In effect
• KS AI Foreign Platforms Ban · In effect
• MT Right to Compute Act · In effect